Method of characterisation of genomic DNA

Details Method of characterisation of genomic DNA Method of characterisation of genomic DNA

1996-05-06

1998-12-29

Campbell, Eggerton A.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 912, C12Q 168, C12P 1934

Patent

active

058539891

ABSTRACT:
The present invention relates generally to a method of characterizing a sample of genomic DNA and to nucleotide sequences employed in the method as well as kits comprising these. In particular the invention involves the use of primers which selectively prime specific type(s) of internal repeat unit in a tandemly repeated region. The method of the invention is particularly useful in forensic or paternity studies and provides individual sample codes suitable for computerized storage on, and retrieval from, a database.

REFERENCES:
patent: 5066584 (1991-11-01), Gyllensten et al.
patent: 5104792 (1992-04-01), Silver et al.
patent: 5175082 (1992-12-01), Jeffreys
Skolnick et al Genomics 2:273-279 (1988).
Mullis et al Cold Spring Harbor Symp. on Quat. Biol pp. 263-273 (1986).
Database WPI, Section Ch, Week 9119, Derwent Pub. Ltd, London, GB; Clars B04f, AN91-140560, XP002010671 A-7,454,171 (Silver J.) 15 May 1990--Abstract.
Mullis et al, "Specific Enzymatic Amplification of DNA In Vitro: The Polymerase Chain Reaction", Cold Harbor Symposia on Quantitative Biology, vol. L1, pp. 263-273 (1986).
Erlich et al, "Recent Advances in the Polymerase Chain Reaction", Science 252(5013):1643-1651 (1991).
Jeffreys et al, "Minisatellite repeat coding as a digital approach to DNA typing", Nature 354:204-29 (1991).
Jeffreys et al, "Repeat Unit Sequence Variation in Minisatellites: A Novel Source of DNA Polymorphism for Studying Variation and Mutation by Single Molecule Analysis", Cell 60:473-485 (1990).
Monckton et al, "Minisatellite Isoallele Discrimination in Pseudohomozygotes by Single Molecule PCR and Variant Repeat Mapping", Genomics 11:465-467 (1991).
Gibbs, "DNA Amplification by the Polymerase Chain Reaction", Anal. Chem. 62:1202-1214 (1990).
U.S. Patent Application Serial No. 07/504,591--Suldiner et al, "RNA Template-Specific Polymerase Chain Reaction".
Honghua Li et al, "Amplifcation and analysis of DNA sequences in single human sperm and diploid cells", Nature 335:414-417 (1988).
Mullis et al, "Specific enzymatic amplification of DNA . . . ", Cold Spring Harber Symposium Qunt. Biol. L1:263-273 (1986).
Weber and May, "Abundant Class of Human DNA Polymorphisms Which Can Be Typed Using the Polymerase Chain Reaction", Am. J. Hum. Genet. 44:388-396 (1989).
Farr et al, "New Variations on the them", Nature 354:184 (1991).

Affiliated with

Also associated with

Rating

Method of characterisation of genomic DNA does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of characterisation of genomic DNA, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of characterisation of genomic DNA will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1423317