Method of changing conformation of a matrix metalloproteinase

Details Method of changing conformation of a matrix metalloproteinase Method of changing conformation of a matrix metalloproteinase

2005-03-22

2005-03-22

Ramsuer, Robert W. (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C544S159000

Reexamination Certificate

active

06869951

ABSTRACT:
The present invention provides a matrix metalloproteinase inhibiting compound having structure (VIII) or a salt, an enantiomer, a diastereomer, a racemate, or a tautomer thereof. In other embodiments, the present invention provides a method of changing the conformation of a matrix metalloproteinase, a method of inhibiting a matrix metal metalloproteinase, and a method of treating osteoarthritis.

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