Drug – bio-affecting and body treating compositions – Extract – body fluid – or cellular material of undetermined... – Blood
Patent
1989-05-11
1993-01-05
Rosen, Sam
Drug, bio-affecting and body treating compositions
Extract, body fluid, or cellular material of undetermined...
Blood
424532, 424530, 424 858, 435 2, 514 2, 514 8, A61K 3514
Patent
active
051769212
ABSTRACT:
Biological compositions are freed of functional polynucletides by treatment of the biological composition with psoralen derivatives under irradiation conditions in which the proteins retain their original physiological activities and any polynucleotide present is rendered inactive. More specifically blood components are decontaminated of viruses by the addition of psoralen and irradiation and thereafter adding glucose.
REFERENCES:
patent: 3874384 (1975-04-01), Deindoerfer et al.
patent: 4112070 (1978-09-01), Harmening
patent: 4124598 (1978-11-01), Hearst et al.
patent: 4160204 (1979-09-01), Hearst et al.
patent: 4321919 (1982-03-01), Edelson
patent: 4327086 (1982-04-01), Fukushima et al.
patent: 4568542 (1986-02-01), Kronenberg
patent: 4572899 (1986-02-01), Walker et al.
patent: 4595653 (1986-06-01), Kronenberg
patent: 4695460 (1987-09-01), Holme
patent: 4748120 (1988-05-01), Wiesehahn
Musajo, et al., Experentia, vol. XXI, pp. 22-24 (1965).
De Mol, et al., Photochemistry and Photobiology, vol. 33, pp. 815-819 (1981).
Veronese, et al., Photochemistry and Photobiology, vol. 36, pp. 25-30 (1982).
De Mol, et al., Chemical Interactions, vol. 95, No. 74467, p. 197 (1981).
De Mol, et al., Photochemistry ad Photobiology, vol. 34, pp. 661-666 (1981).
Veronese, et al., Photochemistry and Photobiology, vol. 34, pp. 351-354 (1981).
Singh, et al., Photochemistry and Photobiology, vol. 28, pp. 539-545 (1978).
Joshi, et al., Biochemical and Biophysical Research Communications, vol. 112, No. 2, pp. 638-646 (1983).
Grossweiner, NCI Monograph, No. 66, pp. 47-54.
Hanson, Medical Virology II, pp. 45-79.
Rodighiero and Dall'Acqua, NCI Monograph, No. 66, pp. 31-42 (1982).
Hyde, et al., Biochemistry, vol. 17, pp. 1251-1257 (1978).
Hanson, et al., J. Gen. Virology, vol. 40, pp. 345-358 (1978).
Swanstrom, et al., J. Gen. Virology, vol. 113, pp. 613-622 (1981).
Redfield, et al., Infec. and Immun., vol. 32, pp. 1216-1226 (1981).
Cremer, et al., J. Clin. Microbiology, vol. 15, pp. 815-823 (1982).
Corash Laurence
Wiesehahn Gary P.
Diamond Scientific Co.
Gil Joseph C.
Rosen Sam
University of California
Whalen Lyndanne M.
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