Method of blocking the SEC receptor

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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A61K 3816

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active

055146538

ABSTRACT:
A method is disclosed for blocking the SEC receptor and also inhibiting the neurotoxic effects of amyloid-.beta. protein by treating SEC receptor-bearing cells with a synthetic inhibitor peptide, e.g. peptide PB145.

REFERENCES:
patent: 5137873 (1992-08-01), Yankner
patent: 5157019 (1992-10-01), Glover et al.
patent: 5164295 (1992-11-01), Kisilevsky et al.
patent: 5175253 (1992-12-01), Fallon et al.
patent: 5187153 (1993-02-01), Cordell et al.
J. Clin. Invest., vol. 90, issued Sep. 1992, Joslin et al, "The Serpin-Enzyme Complex (SEC) Receptor . . . ", pp. 1150-1154.
Brain Research, vol. 651, issued 1994, Khalil et al, "BA.sub.4 25-35 Modulates Substance P . . . ", pp. 227-235.
Perlmutter et al., Proc. Natl. Acad. Sci. USA 87, 3753-3737 (1990).
Perlmutter et al., J. Biol. Chem. 265, 16713-16716 (1990).
Joslin et al., J. Biol. Chem. 266, 21897-21902 (1991).
Yanker et al., Science 250, 279-282 (1990).
Joslin et al., J. Biol. Chem. 266, 11282-11288 (1991).
Yanker et al., N. Engl. J. Med. 325, 1849-1857 (1991).
Shearman et al., Proc. Natl. Acad. Sci. 91, 1470-1474 (1994).
Hansen et al., J. Immunol. Meth. 119, 203-210 (1989).

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