Method of blocking human 5-hydroxytryptamine-2 receptors

Details Method of blocking human 5-hydroxytryptamine-2 receptors Method of blocking human 5-hydroxytryptamine-2 receptors

1995-02-16

1997-10-07

Cintins, Marianne M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

A61K 3144

Patent

active

056748752

ABSTRACT:
N-unsubstituted ergolines specifically bind to human 5-HT.sub.2 receptors, and are thus useful in treating diseases such as depression, hypertension and migraine.

REFERENCES:
patent: 2736728 (1956-02-01), Pioch
patent: 2774763 (1956-12-01), Garbrecht
patent: 4798834 (1989-01-01), Merritt et al.
patent: 5141944 (1992-08-01), Cohen et al.
Pazos et al, European Journal of Pharmacology, 106, 531-538 (1985).
M.P. Johnson, Slide Presentation at Burroughs Wellcome Research Triangle Park, North Carolina, May 3-4, 1992.
Nelson et al. J. Pharmacol. & Exp. Therapeutics, 1993, 265(3), 1272-9.
Misner et al. J. Med. Chem., 1990, 33, 652.
Kao et al., Federation of European Biochemical Societies, 307(3) 324 (1992) .

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