Method of biosynthesis and cells therefor

Details Method of biosynthesis and cells therefor Method of biosynthesis and cells therefor

1984-09-24

1989-06-13

Huleatt, Jayme A.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing alpha or beta amino acid or substituted amino acid...

43525233, 435320, 4351723, 435849, 935 29, 935 41, 935 60, 935 73, C12P 1322, C12N 120, C12N 1500, C12R 119

Patent

active

048392863

ABSTRACT:
An expression vector having two structural genes that form a synthetic operon expressed under the control of a single regulatory sequence. The operon genes correspond to the structural component of naturally occurring genes whose expression is controlled by distinct separate regulatory sequences. The operon genes code for enzymes in a biosynthetic pathway for producing a desired compound, and at least one of those operon genes is feedback derepressed. The vector is used to transform host cells that are cultured to produce the desired product.

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