Method of binding antigens to insoluble polymeric substances

Details Method of binding antigens to insoluble polymeric substances Method of binding antigens to insoluble polymeric substances

1979-07-30

1981-07-21

Woodberry, Edward M.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

260 6, 260 75, 260 9, 260 174ST, 424 12, C08L 8900, C08L 500

Patent

active

042797870

ABSTRACT:
This invention relates to a method of binding antigenically active materials to the surface of water insoluble, hydrophobic polymeric substances which comprises pretreating the water-insoluble hydrophobic polymeric substance with an aldehyde of the formula, OHC--X--CHO, wherein X may be --CH.sub.2).sub.n, wherein n is an integer of from 1 to 10; cycloalkyl, for example, cyclopentyl, cyclohexyl; monocyclic aryl, for example, phenyl, and thereafter contacting the thus treated polymeric material with the purified antigenically active material to be bound thereto. The final products of this invention are employable as diagnostic products.

REFERENCES:
patent: 4045384 (1977-08-01), Dorman
patent: 4119589 (1978-10-01), Horn et al.
patent: 4181636 (1980-01-01), Fischer
patent: 4182695 (1980-01-01), Horn et al.

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