Method of assaying the bioactivity of a thymic extract

Details Method of assaying the bioactivity of a thymic extract Method of assaying the bioactivity of a thymic extract

1987-02-27

1990-01-16

Warden, Robert J.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving viable micro-organism

436172, C12Q 102

Patent

active

048943290

ABSTRACT:
A method of assaying the bioactivity of a thymic extract is disclosed. The disclosed method measures the chemiluminescence of macrophage derived from an immune-deficient mouse after stimulation with the sample thymic extract, phagocytic stimulator, and luminescent detecting solution. A kit suitable for practicing the method is also disclosed.

REFERENCES:
Allen et al., Biochem. Biophys. Research Communic., 69, 245-252, 1976.
Coleman et al., J. Immunol., 130, 2195-2199, 1983.
Coleman et al., J. Immunol, 133, 3121-3127, 1984.
Mellors et al., Cell. Immunol., 110, 391-399, 1987.
Ippoliti et al., 5th European Immunology Meeting, Istanbul, Turkey, June 1-4, 1982, Abstract.
Herbert et al. (E.D.S.), Dictionary of Immunology, 3rd Ed., Blackwell Scientific Publications, Oxford, 1985, p. 114.

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