Method of arresting degeneration of the substantia nigra by high

Details Method of arresting degeneration of the substantia nigra by high Method of arresting degeneration of the substantia nigra by high

1996-04-25

1998-01-13

Kamm, William E.

Surgery: light, thermal, and electrical application

Light, thermal, and electrical application

Electrical therapeutic systems

128898, A61N 100

Patent

active

057073961

ABSTRACT:
A method of preventing further degeneration of the substantia nigra observed in patients with Parkinson's disease. High frequency electrical pulses are supplied to the subthalamic nucleus thereby blocking stimulation of the subthalamic nucleus

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Mark Hallett, "The Plastic Brain," Annals of Neurology, vol. 38, No. 1, J 1995.
C.W. Olanow et al., "The Effect of Deprenyl and Levodopa on the Progression of Parkinson's Disease," Ann. Neurol. 1995;38:771-777.
Stanley J. Appel, "A Unifying Hypothesis for the Cause of Amyotrophic Lateral Sclerosis, and Alzheimer Disease," Ann. Neurol. 1981;10:499-505.
J.T. Greenamyre, "Glutamate-dopamine Interactions in the Basal Ganglia: 1993;91:255-269.
Limousin et al "Effect on parkinsonian signs and symptoms of bilateral subthalamic nucleus stimulation" The Lancet vol. 345 Jan. 14, 1995.
Benabid et al "Long-term suppression of tremor by Chronic stimulation of the ventral intermediate thalamic nucleus" The Lancet, vol. 337, Feb. 16, 1991.
Benabid et al "Vim & STN Stimulation in Parkinson' disease" Abstracts of the Intl Congress of Movement Disorders 1994.

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