Method of applying alpha hydroxy acids for treating striae diste

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...

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A61K 3119

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active

054440912

ABSTRACT:
A method is provided to treat striae distensae lesions by topically applying to the skin affected with said lesions an effective amount of a treatment composition containing glycolic acid, preferably by daily application in a pharmaceutically acceptable vehicle, as a cream base, at a concentration of from 15 to 20 percent by weight.

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P. Zheng et al. "Anatomy of Striae", British Journal of Dermatology, 112:185-193 (1985).
P. Nigam, "Striae Cutis Distensae", Inter Journal of Dermatology, Sep. 1989 pp. 426-428.
Thomas et al. "The Therapeutic Uses of Topical Vitamin A Acid", Journal of the American Academy of Dermatology, 4:505-513 (1981).
"Treatment of Striae Distensae with Topical Tretinoin" J. Dermatol Surg Oncol 16:3, Mar. 1990, pp. 267-269.
Lavker etal. "Effects of Topical Ammonium Lactate on Cutaneous Atropy from a Potent Topical Corticosteroid", Journal of the American Academy of Dermatology, (1992) pp. 535-543.

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