Method of and solution for treating glaucoma

Details Method of and solution for treating glaucoma Method of and solution for treating glaucoma

1991-02-26

1993-05-18

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

514180, 514395, 514913, A61K 3156, A61K 31415

Patent

active

052121682

ABSTRACT:
A method for treating glaucoma consisting of exposing the eye to a corticosteroid and an alpha or a beta adrenergic agent to the eye which acts to decrease ocular pressure. Useful adrenergic agents include beta agonist antagonists, including, for example, epinephrine, dipivalyl epinephrine, betaxolol, levobunolol, timolol, and an alpha adrenergic agonist, including apraclonidine hydrochloride. Useful steroids, which are preferably applied topically, include dexamethasone, prednisolone, cortisone, and triamcinolone. The beta adrenergic agent is administered at a concentration between 10% and 20% of the concentration that the agent is administered in its normal use. The corticosteroid is administered at a concentration between 5% and 10% of the concentration that the corticosteroid is administration in its normal use.

REFERENCES:
patent: 4904649 (1990-02-01), Schwartz
The Merck Index Eleventh Edition (1989), pp. 118-119.

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