Method of and apparatus for immune analysis

Details Method of and apparatus for immune analysis Method of and apparatus for immune analysis

1996-01-26

1998-05-12

Spiegel, Carol A.

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

Carrier is inorganic

422 8205, 422 8209, 422 8211, 435962, 436154, 436524, 436536, G01N 33553

Patent

active

057504105

ABSTRACT:
A total reflection cell has a total reflection prism on at least one surface thereof. A mixed solution containing a gold colloid labelled antibody which is adsorbed on a gold colloid is stored in the total reflection cell, and a sample solution containing an antigen causing antigen-antibody reaction with the antibody is added thereto for forming a gold colloid labelled immune complex. A measuring beam is introduced into the total reflection prism from an incident optical system at an angle .theta. of incidence causing total reflection and an outgoing beam from the total reflection prism is received by a measuring optical system, thereby measuring absorption by the gold colloid labelled immune complex and carrying out qualification and determination of the antigen.

REFERENCES:
patent: 4208185 (1980-06-01), Sawai et al.
patent: 5112129 (1992-05-01), Carrabba et al.
patent: 5376556 (1994-12-01), Tarcha et al.
patent: 5468644 (1995-11-01), Stephenson et al.
patent: 5607643 (1997-03-01), Xiaoning et al.

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