Method of and apparatus for diagnostic DNA testing

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

435 911, C12P 1934

Patent

active

058144919

ABSTRACT:
An assay for detecting mutations in genes by a two-step multiplex polymerase chain reaction amplification followed by preferably two-dimensional electrophoretic separation of the fragments on the basis of both size and base pair sequence.

REFERENCES:
patent: 4683202 (1987-07-01), Mullis
patent: 5068176 (1991-11-01), Vijg et al.
patent: 5340728 (1994-08-01), Grosz et al.
patent: 5364759 (1994-11-01), Caskey et al.
Berg et al. (1995) Clin. Chem. 41:1461-66.
Repp et al. (1995) Leukemia 9:210-15.
Repp et al. (1993) J. Clin. Microbiol. 31:1095-1102.
Avner et al. (1994) Hum. Reprod. 9:1676-80.
Dreesen et al. (1995) Molecular Hum. Reprod. 10:743-748.
Tenorio et al. (1993) J. Virol. Methods 44:261-69.
Reubel et al. (1995) Arch. Virol. 140:1049-60.
Levinson et al. (1992) Reliable gender screening for human preimplantation embryos using multiple DNA target sequences. Human Reproduction 7:1304-13.
Zazzi et al. (1993) Simultaneous Amplification of Multiple HIV-1 DNA sequences from clinical specimens by using nested-primer polymerase chain reaction. AIDS Res. Human Retroviruses 9:315-320.
Uitterlinden and Vijg (1990) Appl. Theoret. Electrophor., 1:175-9.
Vijg et al. (1994) Mutation Res., 308:205-214.
Meerman et al. (1993) Am. J. Hum. Genet., 53:1289-97.
Edwards and Gibbs (1994) PCR Meth. Appl., 3:s65-s75.
Bell and Byers (1983) Anal. Biochem., 130:527-35.
Blanquet et al. (1993) Hum. Mol. Genet., 2:975-979.
Uitterlinden et al. (1991) Electrophoresis, 12:119-134.
Uitterlinden et al. (1989) Proc. Natl. Acad. Sci. USA, 86:2742-46.
Poddar and Maniloff (1989) Nucl. Acids Res., 17:2889-2895.
Myers et al. (1987) Methods Enzymol., 155:501-527.
Myers et al. (1985) Nucl. Acids Res., 13:3131-3145.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method of and apparatus for diagnostic DNA testing does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of and apparatus for diagnostic DNA testing, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of and apparatus for diagnostic DNA testing will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-685482

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.