Chemistry: analytical and immunological testing – Including chromatography
Patent
1984-12-26
1987-06-09
Marcus, Michael S.
Chemistry: analytical and immunological testing
Including chromatography
73 611C, 2101982, 2103211, 210649, 210656, 422 61, 422 70, 436150, 436175, 436178, G01N 3014, G01N 3096, B01D 1300
Patent
active
046720421
ABSTRACT:
An ion-chromatography system for analyzing one or more ionic species of a given polarity in solution, the system comprising an ion-exchange material reactive with such species, an eluant fluid, means for adding the eluant fluid and ionic species to the separation column, a stripper column and a detector. The eluant fluid includes at least a pair of electrically neutral molecular species reactive with one another to provide ionic constituents, the molecular species being in substantial equilibrium with the ionic constituents. The stripper column is positioned at the outlet of the separation column to receive the eluant fluid from the latter and reduce the concentration of the ionic constituents in the eluant fluid. The stripper column includes a conduit relatively permeable to the neutral molecular species in the eluant and relatively impermeable to the ionic constituents. Means are also provided for removing any of the neutral species that permeate the conduit, whereby a concentration gradient is established across the conduit. The detector is provided to quantitatively measure the chromatographically separated ionic species in the eluant discharged from the stripper column.
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Goldring Lionel S.
Riseman John H.
Ross, Jr. James W.
Hill Jr. Robert J.
Marcus Michael S.
Orion Research Puerto Rico, Inc.
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