Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2006-03-13
2010-12-28
Myers, Carla (Department: 1634)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S091200, C536S023100, C536S023500
Reexamination Certificate
active
07858303
ABSTRACT:
A method of analyzing breast cancer susceptibility or resistance, comprising the steps of obtaining a DNA sample from a patient, genotyping the sample for the presence of the minor allele of single nucleotide polymorphisms rs6476643 or rs2182317, and correlating the identity of the allele with risk assessment data is disclosed.
REFERENCES:
patent: 2004/0014097 (2004-01-01), McGlennen et al.
NCBI Single Nucleotide Polymorphism (SNP) Database. rs2182317, ss3119497, Jun. 7, 2001.
Hirschhorn et al. Genetics in Medicine. 2002. 4(2): 45-61.
Pharoah et al. PLoS Genetics. Mar. 2007. 3(3): 0401-0406.
Young et al. British Journal of Cancer (1999) 81: 141-143.
Ameyaw et al. Journal of the National Cancer Institute. 2000. 92: 1947.
Mavaddat et al. Cancer Epidemiol Biomarkers Prev. 2009. 18: 255-259.
PCT/US2006/008958 International Search Report mailed May 3, 2007.
Lan Hong et al: “Genetic loci controlling breast cancer susceptibility in the Wistar -Kyoto rat”, Genetics, vol. 157, No. 1, Jan. 2001, pp. 331-339.
Samuelson David J et al: “Fine mapping reveals multiple loci and a possible epistatic interaction within the mammary carcinoma susceptibility quantitative trait locus, Mcs5”, Cancer Research, vol. 65, No. 21, Nov. 2005, pp. 9637-9642.
Cotroneo M S et al: “The Mcs7 quantitative trait locus is associated with an increased susceptibility to mammary cancer in congenic rats and an allele-specific imbalance”, Oncogene, vol. 25, No. 36, Aug. 2006, pp. 5011-5017.
Polyak, K.: “Breast cancer gene discovery”, Expert Reviews in Molecular Biology, Aug. 2002, pp. 1-18.
Hill et al., “Linkage Disequilibrium in Finite Populations”, Theoretical and Applied Genetics, 38, 226-231, 1968.
VanLiere et al., “Mathematical Properties of the r2 Measure of Linkage Disequilibrium”, Theoretical Population Biology, 74, 130-137, 2008.
Samuelson et al., “Rat Mcs5a is a Compound Quantitative Trait Locus with Orthologous Human Loci that Associate with Breast Cancer Risk”, PNAS, 104, 15, 6299-6304, 2007.
Gould Michael N.
Haag Jill D.
Nelson Stephanie E.
Samuelson David J.
Myers Carla
Quarles & Brady LLP
Wisconsin Alumni Research Foundation
LandOfFree
Method of analyzing breast cancer susceptibility and resistance does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method of analyzing breast cancer susceptibility and resistance, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of analyzing breast cancer susceptibility and resistance will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4220152