Method of analyzing biological, liquid specimens for antigens or

Details Method of analyzing biological, liquid specimens for antigens or Method of analyzing biological, liquid specimens for antigens or

1977-02-16

1980-02-05

Marantz, Sidney

Chemistry: physical processes

Physical processes

Crystallization

232306, 424 1, 424 8, 424 12, 435 7, G01N 3316, G01N 2138, G01N 3114

Patent

active

041870751

ABSTRACT:
A human body fluid is analyzed for the presence of one member of the group consisting of an antigen and an antibody capable of specifically combining with the antigen by depositing a specimen of the fluid to be analyzed on an inert solid substrate and by volatilizing the water in the specimen under mild conditions which leave the one member as a deposit on the surface of the substrate. The surface then is contacted with the other member, which carries a labeling agent, for a period sufficient for combining the members if the one member is present. Any amount of the labeled member not combined with the one member thereafter is removed, and a sensible signal indicative of the presence of labeing agent on the substrate is generated.

REFERENCES:
patent: 3646346 (1972-02-01), Catt
patent: 3790663 (1974-02-01), Garrison
patent: 3826619 (1974-07-01), Bratu
patent: 3843324 (1974-10-01), Edelman
patent: 4016043 (1977-04-01), Schuurs
patent: 4020151 (1977-04-01), Bolz

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