Method of administering a vaccine comprising tritrichomonas foet

Details Method of administering a vaccine comprising tritrichomonas foet Method of administering a vaccine comprising tritrichomonas foet

1994-02-07

1999-01-05

Caputa, Anthony C.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

4242691, 4242781, 530412, 530414, 530424, A61K 39002, C07K 1444, A23J 320

Patent

active

058559027

ABSTRACT:
A subunit vaccine for Tritrichomonas foetus and method for preparing such vaccine for use in immunizing and treating animals is provided. The method disclosed involves separating out the antigens by centrifuging homogenized Tritrichomonas foetus cells, preferably at about 830.times.g for about 15 minutes, solubilizing the antigen with an nonionic detergent and completing with saponin. Topical administration, such as intravaginal or intrapretutial administration, of such vaccine preparation in conjunction with subcutaneous administration in combination with other adjuvants is effective to eliminate infection.

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