Method of administering a biologically active substance

Details Method of administering a biologically active substance Method of administering a biologically active substance

1993-11-15

1995-06-27

Warden, Jill

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 2, 514 4, 530303, 530307, 530311, 530313, A61K 3800, A01N 3718, C07K 500, C07K 700

Patent

active

054280060

ABSTRACT:
A method for administering a therapeutically effective amount of a biologically active substance to the circulatory system of a mammal including administering a pharmaceutical composition having a total volume of 1-1000 .mu.1 to a nasal mucosal membrane of the mammal, the pharmaceutical composition including the therapeutically effective amount of the biologically active substance dissolved or suspended in a volume of 1-1000 .mu.1 of a n-glycofurol-containing vehicle including at least one n-glycofurol represented by the formula: ##STR1## wherein n is from 1 to 8, so that upon administration of the pharmaceutical composition to the nasal mucosal membrane, absorption of the biologically active substance through the mucosal membrane and into the blood stream of the mammal rapidly takes place and thereby allows the biologically active substance to exert its therapeutic effect.

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