Method of acylation of phloroglucinol

Details Method of acylation of phloroglucinol Method of acylation of phloroglucinol

1976-05-05

1977-10-11

Morgenstern, Norman

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260586R, 260586C, 260586P, 260590E, 260591, 260592, C07C 4500

Patent

active

040535177

ABSTRACT:
A method of acylation of phloroglucinol in the presence of a Friedel Crafts catalyst which is effected in the presence of nitromethane and dichloromethane so as to produce an acylphloroglucinol. The acylphloroglucinol is reacted with a compound selected from .gamma.,.gamma.-dimethyl allyl bromide and 2-methyl-but-3-ene-2-ol in the presence of a weak Lewis acid and in an organic solvent to produce a 4-desoxyhumulone which is then oxidized to produce a corresponding humulone.

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