Chemistry: analytical and immunological testing – Including chromatography
Patent
1995-05-24
1998-01-13
Snay, Jeffrey
Chemistry: analytical and immunological testing
Including chromatography
436 71, G01N 3002
Patent
active
057078734
ABSTRACT:
A method of assessing the mixed lipid transport properties of a drug is provided. The method includes providing a mixed lipid composition which incorporates a drug in colloidal particles, applying the particles to a size exclusion chromatography column, eluting free drug and drug incorporated into mixed lipid particles from the column, and determining the elution profiles of the free drug and the drug incorporated into mixed lipid particles. Drugs which elute with the mixed lipid particles are considered to have stable transport properties when incorporated into the mixed lipid particles.
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Ludlow Jan M.
Snay Jeffrey
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