Method of accelerating the proliferation of emdothelial cells wi

Details Method of accelerating the proliferation of emdothelial cells wi Method of accelerating the proliferation of emdothelial cells wi

1994-06-30

1995-12-26

Prescott, Arthur C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514 12, A61K 31175, A61K 31165, A61K 3112

Patent

active

054788218

ABSTRACT:
A method of accelerating the proliferation of endothelial cells with inhibition of NO synthases in warm-blooded animals comprising administering to warm-blooded animals an amount of at least one compound selected from the group consisting of a .beta.-naphthoquinone of the formula ##STR1## wherein R is selected from the group consisting of --NH--CO--NH.sub.2, --NH--C0--CH.sub.3 and --0H and their non-toxic, pharmaceutically acceptable acid addition salts in an amount sufficient to accelerate the proliferation of endothelial cells.

REFERENCES:
patent: 3758520 (1973-09-01), Beaudet
M. Ploin, "Etioven 10 mg., Medicament De L'annee", La Gazette Medicale, vol. 100, No. 20, p. 30, May 1993.
Laborit et al, "Effets de la Mono-Semicarbazone . . . Hemorragique Experimental", Agressologie, vol. 12, pp. 25-30, (1971).

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