Method forming protease inhibitor synthetic intermediates

Details Method forming protease inhibitor synthetic intermediates Method forming protease inhibitor synthetic intermediates

1995-05-16

1997-04-08

Higel, Floyd D.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

5483137, 558408, 558452, 560 34, 564 32, 564 61, 564152, 564159, 564197, 564198, 564343, 564355, 564356, 564357, 564358, 564342, 564418, 564495, 564503, C07C22934, C07C21528, C07C21300, C07C22702, C07D40312

Patent

active

056189664

ABSTRACT:
The present invention relates to a method of forming a 1,3-diamino-3-substituted-2-propanol chemical intermediate from which various chemicals, such as selected protease-inhibitors and other drugs, as well as polymers, can be synthesized.
This method includes contacting a nitromethyl amino acid compound with at least one reducing agent to form the 1,3-diamino-3-substituted-2-propanol chemical intermediate.

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