Drug – bio-affecting and body treating compositions – Designated inorganic nonactive ingredient or elemental... – Siliceous or calcareous material
Patent
1981-06-01
1986-07-08
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Designated inorganic nonactive ingredient or elemental...
Siliceous or calcareous material
424 49, A61K 716
Patent
active
045993637
ABSTRACT:
A process is provided for the rapid wetting and dispersing of powders suitable for obtaining an essentially gas-free paste, particularly in the manufacture of toothpaste compositions. The process consists of charging a vacuum mixer with the appropriate liquids, and subjecting the liquids to a continuous vacuum that will draw the powders in at the bottom of the mixer in an area of high turbulence generated by a high speed mixing device. The turbulence caused by the expanding air entrained in the powder as it enters the vacuum and generated by the impeller of a high speed mixer, wets the powders very rapidly, inhibits the formation of undesirable lumps, and essentially minimizes loss of powders to the vacuum system. In addition, little or no air is entrained in the resulting paste.
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Riegel Chemical Process Machinery, 2nd Ed. (1953), Reinhold, NY, TP157R 53 (1953), pp. 264-307, "Mixing".
DeMasi Dominick F.
Miles, Jr. John J.
Farrell James J.
Lever Brothers Company
Rose Shep K.
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