Method for visualizing large-scale protein interaction data

Details Method for visualizing large-scale protein interaction data Method for visualizing large-scale protein interaction data

2007-10-09

2007-10-09

Borin, Michael (Department: 1631)

Data processing: measuring, calibrating, or testing

Measurement system in a specific environment

Biological or biochemical

C703S011000

Reexamination Certificate

active

10290432

ABSTRACT:
Disclosed is a method of visualizing large-scale protein interaction data, comprising the steps of (1) producing an initial layout by placing all nodes of protein interaction data on the surface of a sphere by increasing horizontal and vertical angles of polar coordinates; and (2) yielding a graph by iterating a process moving each node of the initial layout to an equilibrium position considering global spring forces between non-adjacent nodes as well as local spring forces between adjacent nodes on a predetermined number of times, by which large-scale protein interaction data is effectively visualized in a three-dimensional space. The method for visualization of the present invention, which is much faster than the conventional algorithms, can be used for interactive analysis, as well as provide an integrated system capable of directly visualizing query results from a protein-protein interaction database.

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