Method for vesicle formation

Details Method for vesicle formation Method for vesicle formation

1989-01-27

1990-06-19

Lovering, Richard D.

Plastic and nonmetallic article shaping or treating: processes

Encapsulating normally liquid material

Liquid encapsulation utilizing an emulsion or dispersion to...

264 41, 424450, 436829, 514 6, 514832, 514833, A61K 4300, A61K 9127, B01J 1302

Patent

active

049351710

ABSTRACT:
A single-vessel method is provided for preparing liposomes in commercial quantities by forming a homogeneous and uniform lipid film in a thin-film evaporator by evaporation of the organic solvent, followed by in situ hydration of the film in an aqueous phase by agitation with the rotor.

REFERENCES:
patent: 2812019 (1957-11-01), Rasmussen
patent: 2863888 (1958-12-01), Schurman
patent: 2927634 (1960-03-01), Gudheim
patent: 3129132 (1964-04-01), Gudheim
patent: 3261391 (1966-07-01), Gudheim
patent: 3346034 (1967-10-01), Donovan et al.
patent: 3468849 (1969-09-01), Rothert
patent: 4065346 (1977-12-01), Evkin
patent: 4073677 (1978-02-01), Noda
patent: 4093479 (1978-06-01), Baird
patent: 4133874 (1979-01-01), Miller et al.
patent: 4153500 (1979-05-01), Feres
patent: 4321106 (1982-03-01), Burkhard et al.
patent: 4485054 (1984-11-01), Mezel
patent: 4526713 (1985-07-01), Chino et al.
patent: 4710266 (1987-12-01), Hayashi et al.
patent: 4738295 (1988-04-01), Genser
patent: 4752425 (1988-06-01), Martin
patent: 4753788 (1988-06-01), Gamble
patent: 4761288 (1988-08-01), Mezel
patent: 4765987 (1988-08-01), Bonte
Chemical Engineers' Handbook, Perry et al., pp. 11-27 to 11-36, 1973.
Artisan Industries, A Brief Summary of Artisan Industries' Capabilities, 1987.
Bangham et al., J. Mol. Biol. 13, 238-252 (1965).
Preparation of Liposomes on the Industrial Scale: Problems & Perspectives Chap. 18 in Liposome Technology, vol. I, G. Gregoriadis, Ed. pp. 248-257 (1984).
Brinkman Laboratory Catalog Describing Buchi Rotary Evaporators, pp. 9-12.
Deamer et al., `Liposome Preparation: Methods and Mechanisms`; in Liposomes, M. J. Ostro ed., Marcel Dekker Inc. (1983), p. 36.

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