Method for vascular embolization

Details Method for vascular embolization Method for vascular embolization

1995-03-22

1996-06-11

Kulkosky, Peter F.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Polymer from ethylenic monomers only

514824, 514834, A61K 31785

Patent

active

055253342

ABSTRACT:
Proposed is a method for vascular embolization of the blood vessel of a patient by introducing an aqueous solution of a specific thermosensitive polymer, which is liquid at low temperatures but causes coagulation when heated up to the body temperature of the patient, into the blood vessel followed by in situ heating of the solution. The thermosensitive polymer found to be suitable for the purpose is a homopolymer or copolymer of an N-substituted (meth) acrylamide monomer having a specified intrinsic viscosity in tetrahydrofuran and gives an aqueous solution capable of exhibiting phase transition from a liquid to a coagulate at a transition temperature of 10.degree. to 37.degree..

REFERENCES:
patent: 4732930 (1988-03-01), Tanaka et al.
patent: 5202352 (1993-04-01), Okada et al.

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