Method for using synthetic analogs of thrombospondin for inhibit

Details Method for using synthetic analogs of thrombospondin for inhibit Method for using synthetic analogs of thrombospondin for inhibit

1990-09-24

1993-03-02

Lee, Lester L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514612, 514616, G61K 3702, G01K 104

Patent

active

051909200

ABSTRACT:
Compounds and compositions comprising fragments and methods for using synthetic analogs of thrombospondin for promoting or inhbiting thrombospondin-like activity are provided.

REFERENCES:
Tuszynski et al., "Isolation and Characterization of Artistasin" J. of Biol. Chem., 262, pp. 9718-9723, 1987.
Henessy, et al., "Complete Thrombospondin MRNA Sequence" J. of Cell Biol, 168, pp. 729-736, 1989.
Tuszynski, et al., "Thrombospondin, a Potentiator of Tumor Cell Metastasis", Cancer Research, 47, 4130-4133, 1987.
Ginburg, et al., "Antistasin, an Inhibitor of Coagulation and Metastasis", J. of Biological Chemistry, 264, pp. 12138-12140, 1989.

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