Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1993-07-07
1996-04-23
Walsh, Stephen G.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 4, 435 721, 435 792, 530319, 436518, 436543, G01N 33567, C12N 999, C12N 918
Patent
active
055102425
ABSTRACT:
An improved device is provided which may be used, e.g. for immunoassay of lipopolysaccharides or for removing LPS pyrogens from aqueous solutions, or for removing LPS endotoxins from wounds. Such device comprises, in combination, a substrate, e.g. plastic, i.e. polystyrene, polycarbonate, polymethylmethacrylate or polyvinyl chloride, or a woven cloth, i.e. a rayon/polyester cloth or a polyester cloth, or a non-woven cloth, i.e. a rayon/polyester cloth, or a polyester cloth, or paper, which is adapted to receive a sample to be tested, and an oligopeptide, or a hydrophobic polypeptide or a polymyxin, e.g. polymyxin B, polymyxin B.sub.1, polymyxin B.sub.2, polymyxin D.sub.1, polymyxin D.sub.2, or polymyxin E, adhered to the substrate.
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Endotoxin-Polymyxin Complexes in an Improved Enzyme-Linked Immunosorbent assay for IgG Antibodies in Blood Donor Sera to Gram-Negative Endotoxin Core Glycolipids, B. Scott et al, Vox Sang, vol. 52, pp. 272-280, 1987.
Blais Burton W.
Yamazaki Hiroshi
Kemmerer Elizabeth C.
Walsh Stephen G.
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