Method for using CEST contrast agents in MRI

Details Method for using CEST contrast agents in MRI Method for using CEST contrast agents in MRI

2011-03-29

2011-03-29

Le, Long V (Department: 3768)

Surgery

Diagnostic testing

Detecting nuclear, electromagnetic, or ultrasonic radiation

C600S420000, C324S306000, C324S307000, C324S309000, C424S009360, C424S009361, C424S009364, C424S009365, C424S009362, C540S465000, C540S474000

Reexamination Certificate

active

07917188

ABSTRACT:
A method for mapping a physico-chemical parameter using a chemical exchange saturation transfer contrast agent in Magnetic Resonance Imaging is used with agents having only one exchangeable entity pool, e.g. proton pool, by applying two different RF frequencies for pre-saturation of the contrast agent.

REFERENCES:
patent: 6746662 (2004-06-01), Sherry et al.
patent: 2002/0127182 (2002-09-01), Sherry et al.
patent: 2004/0030239 (2004-02-01), Van Zijl et al.
patent: 2004/0058951 (2004-03-01), Lanza et al.
patent: 1331012 (2003-07-01), None
patent: 0066180 (2000-11-01), None
patent: 2004065385 (2004-08-01), None
Wegh R et al: “CEST With Paramagnetic”,Society for Molecular Imaging, 4th Annual Meeting, 2005, XP002425241.
Zhou et al: “Chemical Exchange Saturation”, Progress in NMR Spectroscopy, Pergamon Press, vol. 48, No. 2-3, pp. 109-136, 2006,XP005458464.
Ward K M et al: “Determination of PH Using Water Protons”,Magnetic Resonance in Medicine, Academic Press,vol. 44, No. 5, pp. 799-802, 2000, XP000969765.
Gillies R J et al: “PH Imaging a Review of PH Measurement Methods”, IEEE Engineering in Medicine and Biology Magazine, IEEE Service Center, vol. 23, No. 5, pp. 57-64, 2004, XP001234807.
Kimura E, et al: “A TRIS(ZnII-1,4,7,10-Tetraazacyclododecane) Complex As a New Receptor”, Journal of American Chemistry Society, 119, pp. 3068-3076, 1997.
A. Heppeler et al: “Radiometal-Labelled Macrocyclic Chelator-Derivatised Somatostatin”, Chem. Eur. J., vol. 5, No. 7, pp. 1974-1981, 1999.

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