Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus
Reexamination Certificate
2006-02-28
2006-02-28
Wehbé, Anne M. (Department: 1632)
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
Genetically modified micro-organism, cell, or virus
C424S093100, C424S093200, C424S277100, C514S04400A, C435S320100, C435S325000
Reexamination Certificate
active
07005126
ABSTRACT:
A method for treating tumors. Through infusion or xenotransplantation of xenogeneic cells, such as infusion of murine cells into the peritoneal cavity of humans, a hyperacute rejection response to the cells is induced. This in turn creates a bystander effect to the tumor. This effect creates tumor regression. This treatment can be used alone or in conjunction with gene therapy or chemotherapy treatments.
REFERENCES:
patent: 5869035 (1999-02-01), Link, Jr. et al.
patent: 6045789 (2000-04-01), Culver et al.
Verma et.al.; Gene therapy- promises, problems and prospects, 1997, Nature, vol. 389: 239-242.
Orkin et.al.; Report and Recommendations of the Panel to Assess the NIH Investment in Research on Gene Therapy, 1995.
Ross et. al.; Gene Therapy in the United States: A Five-Year Status Report, 1996, Human Gene Therapy 7: 1781-1790.
Klatzmann et.al.; A Phase I/II Dose-Escalation Study of Herpes Simplex Virus Type I Thymidine Kinase “Suicide” Gene Therapy for Metastatic Melanoma, 1998, Human Gene Therapy 9: 2585-2594.
Appleton et.al.; Gene Therapy of Cancer V, 1996, Cancer Gene Therapy vol. 3, No. 6.
Link, Jr. et.al.; Eliciting Hyperacute Xenograft Response to Treat Human Cancer: . . . Gene Therapy, 1998, Anticancer Research 18: 2301-2308.
Link et al. (1996) Human Gene Ther., vol. 7, 1161-1179.
Long et al. (1998) Human Gene Therapy, vol. 9, 1165-1172.
Link, Jr. Charles J.
Seregina Tatiana
Human Gene Therapy Research Institute
McKee Voorhees & Sease, P.L.C.
Wehbe Anne M.
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