Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Attached to antibody or antibody fragment or immunoglobulin;...
Patent
1993-02-25
1994-01-11
Lovering, Richard D.
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
Attached to antibody or antibody fragment or immunoglobulin;...
424 9, 424 153, 424 8591, 514908, A61K 4300, A61K 39395
Patent
active
052778940
ABSTRACT:
The invention relates to a method of detecting an Fc receptor-expressing tumor site in an individual by administering to the individual a diagnostically effective amount of detectably-labeled non-specific immunoglobulin or Fc or Fc' fragment thereof, wherein the immunoprotein substantially accumulates at the site when the site bears such a tumor. By using a therapeutically-labeled specific or non-specific immunoglobulin or Fc or Fc' fragment thereof, the tumor may be treated therapeutically.
REFERENCES:
patent: 4444744 (1984-04-01), Goldenberg
patent: 4472509 (1984-09-01), Gansow et al.
patent: 4636380 (1987-01-01), Wong
Kerbel et al., Cell, vol. 3, pp. 105-112 (Oct. 1974).
Ran et al., Chem. Abstracts, vol. 110 (3), 22030b; 1989.
Sunaga et al., Chem. Abstracts, vol. 101 (13) 108241x (Sep. 1984).
Carrasquillo, J. A., et al., Canc. Treat. Rpts. 68:317-328 (1984).
Harwood, P. J., et al., Eur. J. Canc. Clin. Oncol. 21:1515-1522 (1985) (Note: p. 1518 does not exist).
Hayes, D. F., et al., Canc. Res. 46:3157-3163 (1986).
Hwang, K. M., et al., J. Natl. Canc. Inst. 76:849-855 (1986).
Khaw, B. A., et al., J. Nucl. Med. 25:592-603 (1984).
Larson, S. M., J. Nucl. Med. 26:538-545 (1985).
Murray, J. L., et al., J. Nucl. Med 28:25-33 (1987).
Nelp, W. B., et al., J. Nucl. Med. 28:34-41 (1987).
Schirrmacher et al., Journal of Supramolecular Structure 11:105-115 (1979).
Shen et al., Proc. Natl. Acad. Sci. USA 81:1445-1447 (1984).
Shtern, F., et al., J. Nucl. Med. 28:572-573 (1987).
Siden, E., et al., J. Immunol. Meth. 87:251-255 (1986).
Svennevig et al., Br. J. Cancer 45:201-208 (1982).
Titus et al., Proc. Natl. Acad. Sci. USA 78(1):519-523 (1981).
Wright et al., JNCI 78(6):1061-1068 (1987).
Zalcberg., J. R., Am. J. Clin. Oncol. 8:481-489 (1985).
Khaw Ban A.
Rubin Robert H.
Shtern Faina
Strauss H. William
Chapman Lara E.
Lovering Richard D.
The General Hospital Corporation
LandOfFree
Method for tumor detection and treatment does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for tumor detection and treatment, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for tumor detection and treatment will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1629410