Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant...
Patent
1991-07-16
1993-04-06
Stoll, Robert L.
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
424 9, 424 858, 514 2, 5303913, 436173, A61K 4902, A61K 4900
Patent
active
052001784
ABSTRACT:
The invention relates to a method of detecting an Fc receptor-expressing tumor site in an individual by administering to the individual a diagnostically effective amount of detectably-labeled non-specific immunoglobulin or Fc or Fc' fragment thereof, wherein the immunoprotein substantially accumulates at the site when the site bears such a tumor. By using a therapeutically-labeled specific or non-specific immunoglobulin or Fc or Fc' fragment thereof, the tumor may be treated therapeutically.
REFERENCES:
patent: 4331647 (1982-05-01), Goldenberg
patent: 4444744 (1984-04-01), Goldenberg
patent: 4472509 (1984-09-01), Gansow et al.
patent: 4636380 (1987-01-01), Wong
Kerbel et al., Cell, vol. 3, pp. 105-112 (Oct. 1974).
Ran et al., Chemical Abstracts, vol. 110(3), 22030b, 1989.
Sunaga et al., Chemical Abstracts, vol. 101(13), 108241x (Sep. 1984).
Schirrmacher et al., Journal of Supramolecular Structure 11:105-115 (1979).
Zalcberg, J. R., Am. J. Clin. Oncol. 8:481-489 (1985).
Carrasquillo, J. A., et al., Canc. Treat. Rpts. 68:317-328 (1984).
Khaw, B. A., et al., J. Nucl. Med. 25:592-603 (1984).
Nelp, W. B., et al., J. Nucl. Med. 28:34-41 (1987).
Hayes, D. F., et al., Canc. Res. 46:3157-3163 (1986).
Murray, J. L., et al., J. Nucl. Med. 28:25-33 (1987).
Larson, S. M., J. Nucl. Med. 26:538-545 (1985).
Hwang, K. M., et al., J. Natl. Canc. Inst. 76:849-855 (1986).
Shtern, F., et al., J. Nucl. Med. 28:572-573 (1987).
Harwood, P. J., et al., Eur. J. Canc. Clin. Oncol. 21:1515-1522 (1985) (Note p. 1518 does not exist).
Siden, E., et al., J. Immunol. Meth. 87:251-255 (1986).
Svennevig et al., Br. J. Cancer 45:201-208 (1982).
Titus et al., Proc. Natl. Acad. Sci. USA 78(1):519-523 (1981).
Shen et al., Proc. Natl. Acad. Sci. USA 81:1445-1447 (1984).
Wright et al., JNCI 78(6):1061-1068 (1987).
Khaw Ban An
Rubin Robert H.
Shtern Faina
Strauss H. William
Sayala C.
Stoll Robert L.
The General Hospital Corporation
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