Method for treatment or prophylaxis of cardiac disorders

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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424304, 260465D, 260410, 560 42, 560 22, 560 21, A61K 3124, A61K 31275

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active

043871038

ABSTRACT:
A method for the treatment of prophylaxis of cardiac disorders in a mammal, comprising administering to such mammal a short-acting .beta.-blocking compound of the formula: ##STR1## wherein R may be lower alkyl, aryl, or aralkyl; n may be an integer from 0 to about 10; x may be an integer from 1 to 3; Ar may be substituted or unsubstituted aromatic; R.sub.1 may be lower alkyl, or aralkyl; and pharmaceutically accepted salts thereof. Novel compounds possessing short-acting .beta.-adrenergic blocking activity are also disclosed.

REFERENCES:
patent: 3459782 (1969-08-01), Koppe et al.
patent: 3644469 (1972-02-01), Koppe et al.
patent: 3663607 (1972-05-01), Barrett et al.
patent: 3872147 (1975-03-01), Koppe et al.
O'Donnell et al., J. Pharm. Sci., vol. 68, pp. 1236-1238 (1979).
Cutting, Handbook of Pharmacology, Meredith Publishing Co., 4th Ed., pp. 604-607, 1969.

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