Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1980-11-28
1983-09-20
Reamer, James H.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
560 74, 560 73, 560 56, 560 49, 560110, 560100, 560 20, 260465D, 424304, A61K 3124, C07C10148
Patent
active
044056427
ABSTRACT:
A method for the treatment or prophylaxis of cardiac disorders in a mammal, comprising administering to such mammal a short-acting .beta.-blocking compound of the formula: ##STR1## wherein X is an ester-containing group; R may be lower alkyl, aralkyl or an ester-containing group; R.sub.1 may be lower alkyl; and Ar may be substituted or unsubstituted aromatic; or a pharmaceutically acceptable salt thereof. Novel compounds possessing short acting .beta.-adrenergic blocking activity are also disclosed.
REFERENCES:
patent: 3501769 (1970-03-01), Crowther et al.
patent: 4313889 (1982-02-01), Boder
Tatsuno et al., J. Med. Chem., vol. 20, pp. 394-397 (1977).
Cutting, Handbook of Pharmacology, 4th Ed., Meredith Publishing Co., N.Y., pp. 604-607, 1969.
Borgman Robert J.
Erhardt Paul W.
Kam Sheung-Tsam
O'Donnell John P.
American Hospital Supply Corporation
Reamer James H.
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