Drug – bio-affecting and body treating compositions – Extract – body fluid – or cellular material of undetermined...
Patent
1998-06-18
2000-12-26
Salimi, Ali
Drug, bio-affecting and body treating compositions
Extract, body fluid, or cellular material of undetermined...
424522, 424548, 424553, 424572, A61K 3500, A61K 3534, A61K 3512
Patent
active
061655155
ABSTRACT:
A therapeutic agent for osteoporosis brought about by a decrease in estrogen comprises an extract from inflammatory rabbit skin inoculated with vaccinia virus as an effective component. In ovariectomized rats, a model animal for osteoporosis brought about by a decrease in estrogen, the extract from inflammatory rabbit skin inoculated with vaccinia virus has an excellent action for maintaining bone volume and bone strength. The therapeutic agent containing the extract as an active component is very useful for treatment and prevention of osteoporosis brought about by a decrease in estrogen which is frequently caused by menopause or ovariectomy in women. The extract from inflammatory rabbit skin inoculated with vaccinia virus has a high safety profile even when administered for a long term.
REFERENCES:
patent: 3959566 (1976-05-01), Pangonis
patent: 4036787 (1977-07-01), Blount
patent: 4039474 (1977-08-01), Feistel et al.
patent: 4056937 (1977-11-01), Suzuki
patent: 4089883 (1978-05-01), Blount
patent: 4138421 (1979-02-01), Blount
patent: 4863518 (1989-09-01), Blount
patent: 4985254 (1991-01-01), Konishi et al.
patent: 4985354 (1991-01-01), Toyomaki et al.
patent: 5013558 (1991-05-01), Konishi
patent: 5057324 (1991-10-01), Shibayama et al.
patent: 5127994 (1992-07-01), Johansson
patent: 5227089 (1993-07-01), Hasegawa et al.
patent: 5534509 (1996-07-01), Konishi et al.
patent: 5560935 (1996-10-01), Konishi et al.
patent: 5658896 (1997-08-01), Konishi et al.
patent: 5807951 (1998-09-01), Konishi et al.
Chemical Abstracts, vol. 106, No. 10, Mar. 9, 1987, Srivastava et al., XP002096181.
Patent Abstracts of Japan, vol. 017, No. 225 (C-1055), May 10, 1993 & JP 04360838.
Database WPI Section Ch, Week 9624, Derwent, XP002113090 & CN 1 096 180, Dec. 14, 1994, abstract.
Database BIOSIS, XP-002113089, Li S-Y, et al. Studies on the Protective Action of Silicon Compound of Equisetum Against Experimental Liver Injury in Rats and Mice & Zhongguo Yaolixue Yu Dulixue Zazhi. ISSN; 1000-3002, abstract.
Zhao C, et al., "Determination of water soluble silicon from herbal drugs", Chung Kuo Chung Yao Tsa Chih, vol. 15, No. 9, 1990, pp. 555-556.
Paslawska et al., "Studies on the Optimum Conditions of Extraction of Silicon Species from Plants With Water", Planta Medica, vol. 29, No. 1, 1976, pp. 72-79, & XP002113087.
Piekos et al., "Studies on the Optimum Conditions of Extraction of Silicon Species from Plants With Water", Planta Medica, vol. 27, 1975, pp. 145-150, XP002113088.
Database WPI, Section Ch, Week 9411, Derwent, XP002113091 & RU 2003338 C, Nov. 30, 1993, abstract.
Patent Abstracts of Japan, vol. 014, No. 254 (C-0724), May 31, 1990 & JP 02073020, abstract.
"Drug for Food Poisoning," Patent Abstracts of Japan, vol. 11, No. 371 (C-462), Dec. 3, 1987 & JPA62145022 (Sofuto Shirika) Jun. 29, 1987, abstract.
"Adsorbent For Peroxylipid," Patent Abstracts of Japan, vol. 15, No. 474 (C-890), Dec. 3, 1991 & JPA3204803 (Shiscido Co., Ltd.) Sep. 6, 1991, abstract.
The Merck Index, 9th ed. 1976, No. 7456, 8443, 8233-8243 & 5514-5515.
Fujii, Y., et al., "Biological Overview of HIV Accessory Protein Nef," Saibo Kogaku, vol. 16, No. 1, pp. 94-99 (1997).
Derwent Publications Ltd., London, GB: AN 82-10241J, "Drug for Cultivated Fish," & JP A57183720 (Mitani J.), Nov. 12, 1982, abstract.
Abbasi-Jahromi et al., "Bone Quality Factor Analysis: A New Noninvasive Technique for the Measurement of Bone Density and Bone Strength," Journal of Bone and Mineral Research, vol. 11, No. 5, 1996, pp. 594-599.
Richards, et al., "Normal Age-Related Changes in Fluoride Content of Vertebral Trabecular Bone--Relation to Bone Quality," Bone, vol. 15, No. 1, 1994, pp. 21-26.
Sogaard, et al., "A Comparison of the Effects of Two Anabolic Agents (Fluoride and PTH) on Ash Density and Bone Strength Assessed in an Osteopenic Rat Model," Bone, vol. 20, No. 5, May 1997: 439-449.
Ke et al., "Prostaglandin E.sub.2 Increases Bone Strength in Intact Rats and in Ovariectomized Rats With Established Osteopenia," Bone, vol. 23, No. 3, Sep. 1998:249-255.
Takenoka, t. et al, "Influence of Neuroptropin on Thymic Microenviromental Abnormalities of NZB Mice", Int. J. Immunotherapy, XI(2), pp. 49-56 (1995).
"Drugs in Japan, Ethical Drugs", Yagkugo Jihlo Co., Ltd, 1994, p. 1, 434.
Yokoi, et al., "Effect of Degree of Polymerization of Silicic Acid on the Gastrointestinal Absorption of Silicates in Rats", Chem. Pharm. Bull., vol. 27, No. 8, 1979, pp. 1733-1739.
Konishi Jin-emon
Matsuyama Toshikatsu
Nippon Zoki Pharmaceutical Co. Ltd.
Salimi Ali
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