Method for treating wounds using modified hyaluronic acid crossl

Details Method for treating wounds using modified hyaluronic acid crossl Method for treating wounds using modified hyaluronic acid crossl

1998-02-24

2000-08-01

Fonda, Kathleen K.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

A61K 31715

Patent

active

060967277

ABSTRACT:
This invention describes a method for preparing water-insoluble biocompatible gels, films and sponges by reacting hyaluronic acid, or a salt thereof, with a carbodiimide in the absence of a nucleophile or a polyanionic polysaccharide. The water-insoluble gels, films and sponges of this invention may be used as surgical aids to prevent adhesions of body tissues and as drug delivery vehicles.

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patent: 4973493 (1990-11-01), Guire
patent: 5017229 (1991-05-01), Burns et al.
patent: 5128326 (1992-07-01), Balazs et al.
patent: 5527893 (1996-06-01), Burns et al.
Kuo, Jing-wen, "Syntheses and Properties of Hyaluronic Acid Modified by Designed Carbodiimides," Dissertation Abstracts International, 50(12):5626 (1990) month not available.

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