Method for treating unstable angina pectoris

Details Method for treating unstable angina pectoris Method for treating unstable angina pectoris

2006-05-30

2006-05-30

Wax, Robert A. (Department: 1653)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C514S002600, C530S359000

Reexamination Certificate

active

07053049

ABSTRACT:
The invention relates to the use of reconstituted HDL for improving the endothelial function in patients suffering from hypercholesterolaemia and for treating or preventing acute coronary diseases such as unstable angina pectoris.

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patent: WO 01/13939 (2001-03-01), None
patent: WO 01 38395 (2001-05-01), None
Tsutsumi et al., “The Novel Compound NO-1886 Increases Lipoprotein Lipase Activity with Resulting Elevation of High Density Lipoprotein Cholesterol . . . ,” J. Clin. Invest., vol. 92, Jul. 1993, pp. 411-417.
Paul Dimayuga et al., “Reconstituted HDL Containing Human Apolipoprotein A-1 Reduces VCAM-1 Expression and Neointima Formation Following Periadventitial Cuff-Induced Carotid Injury in apoE Null Mice”, Biochemical and Biophysical Research Communications (1999), 264(2), 465-468, XP002218783.
Lukas E. Spieker et al., “High-density liproprotein restores endothelial function in hypercholesterolemic men.” Circulation, (Oct. 31, 2000), vol. 102, No. 18, Supplement, pp. II.315-II.316.
P.G. Lerch et al., “Reconstituted high density lipoprotein (rHDL) modulates platelet activity in vitro and ex vivo”, Thrombosis and Haemostasis, (Aug. 1998) 80(2) 316-20 XP008009389.
R. Moudry et al., “Reconstituted high density lipoprotein modulates adherence of polymorphonuclear leukocytes to human endothelial cells”, Shock (Mar. 1997) 7 (3) 175-81 XP008009425.

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