Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1989-06-21
1990-08-21
Hollrah, Glennon H.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514473, 549313, A61K 3134, C07D30728
Patent
active
049508180
ABSTRACT:
A novel and useful method for treating and/or preventing ulcer in human beings is provided which comprises administering an effective amount of a pharmaceutical composition comprising at least one of the conjugated .gamma.-oxybutenolide compounds represented by the general formula: ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 are the same or different and represent hydrogen atoms, alkyl groups, hydroxyl groups, alkoxy groups, nitro groups, cyano groups or halogen atoms; and optionally at least one pharmaceutically acceptable carrier.
REFERENCES:
patent: 4797417 (1989-01-01), Okamoto et al.
Ito et al., "Synthesis and Spectral Characteriztion of .gamma. Hydroxy-.DELTA..alpha..beta.-Butenolides Possessing a Conjugated Substituent in the .beta.-Position", CA 107:237037h.
Ito Masayoshi
Kido Yoichi
Tamai Yoshin
Torihara Masahiro
Yamahara Johji
Hollrah Glennon H.
Kuraray Company Ltd.
Owens A. A.
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