Method for treating tumors with UDPG

Details Method for treating tumors with UDPG Method for treating tumors with UDPG

1993-03-08

1997-05-06

Rollins, John W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514256, 514261, 514262, A61K 3170, A61K 31505, A61K 3152

Patent

active

056271611

ABSTRACT:
UDPG shows tumor-specific inhibition of PRPP and this suggests that this action might prove to be useful in combination therapy with inhibitors of purine and pyrimidine nucleotide synthesis in various rescue regimens. High levels of PRPP in tumors were greatly affected by treatment with UDPG.

REFERENCES:
patent: 3717547 (1973-02-01), Nakayama et al.
patent: 3787392 (1974-01-01), Ulrich et al.
patent: 3803125 (1974-04-01), Ulrich et al.
Chiesara et al Chem Abst. 94:58307n, 1981.
Klohs et al., Journal of Cellular Phsyology, vol. 119, Apr. (1984), pp. 23-28.
Shur et al., Developmental Biology, vol. 73, (1979), pp. 178-181.
Keppler, Cancer Research, vol. 37, Mar. (1977), pp. 911-917.
Krug et al., Biochem. Journal, vol. 217, (1984), pp. 701-708.
Roussett et al., Cancer Research, vol. 44, No. 1, Jan. (1984), pp. 154-160.
Weckbecker et al., Biochemical Pharmacology, vol. 33, No. 14, (1984), pp. 2291-2298.
Granzow et al., The Journal Of Cell Biology, vol. 89, Jun. (1981), pp. 475-484.
Keppler et al., Adv. Enzyme Regul., vol. 23, (1985), pp. 61-79.
Keppler et al., Adv. Enzyme Regul., vol. 24, (1985), pp. 417-424.

Affiliated with

Also associated with

Rating

Method for treating tumors with UDPG does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for treating tumors with UDPG, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for treating tumors with UDPG will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2132702