Method for treating thin samples on a surface employing capillar

Details Method for treating thin samples on a surface employing capillar Method for treating thin samples on a surface employing capillar

1985-09-13

1988-03-15

Marcus, Michael S.

Chemistry: analytical and immunological testing

Including sample preparation

Volumetric liquid transfer

7386472, 118421, 422100, 436 63, 427 2, 427 4, G01N 112

Patent

active

047313358

ABSTRACT:
Liquid is applied to a thin sample on a first surface (e.g., a specimen on a microscope slide) by maintaining a second surface parallel to the first to provide a gap therebetween and contacting an edge of the gap with a discrete aliquot of liquid. The liquid can migrate by capillary action into contact with the thin sample, preferably upward from horizontally extending linear edges of the surfaces. Liquid can also be removed by contacting the gap edges with absorbent material. Also disclosed are apparatus for holding a plurality of such surfaces in a vertically extending array and apparatus for holding a plurality of liquid droplets beneath the array. One apparatus can be moved relative to the other to contact the lower gap edges with droplets.

REFERENCES:
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patent: 4447140 (1984-05-01), Campbell et al.
patent: 4549952 (1985-10-01), Columbus

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