Method for treating the symptoms of chronic stress-related disor

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514 2, 514 12, 435 691, 530333, 530324, 530303, A01N 4342

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060253681

ABSTRACT:
Methods are provided for treating or alleviating the symptoms of subjects with psychological disorders, metabolic disorders, chronic stress-related disorders, sleep disorders, conditions associated with sexual senescence, aging, or premature aging by treating such subjects with IGF either alone or complexed with IGFBP-3. Methods for increasing the levels of DHEA or DHEAS and treating or alleviating the symptoms of subjects with disorders characterized by low levels of DHEA or DHEAS by administering effective amounts of IGF alone or complexed with IGFBP-3 are also provided. Methods for increasing the level of T4 and treating or alleviating the symptoms of subjects with disorders characterized by low levels of T3 or T4 by administering effective amounts of IGF alone or complexed with IGFBP-3 are additionally provided.

REFERENCES:
patent: 4835147 (1989-05-01), Roberts
patent: 4988675 (1991-01-01), Froesch et al.
patent: 5068224 (1991-11-01), Fryklund et al.
patent: 5077284 (1991-12-01), Loria et al.
patent: 5093317 (1992-03-01), Lewis et al.
patent: 5106832 (1992-04-01), Froesch et al.
patent: 5128320 (1992-07-01), Hanh et al.
patent: 5162198 (1992-11-01), Eich et al.
patent: 5187151 (1993-02-01), Clark et al.
patent: 5200509 (1993-04-01), Spencer et al.
patent: 5202119 (1993-04-01), Clarke et al.
patent: 5273961 (1993-12-01), Clark
patent: 5407684 (1995-04-01), Loria et al
patent: 5407913 (1995-04-01), Sommer et al.
patent: 5407927 (1995-04-01), Morales et al.
patent: 5420112 (1995-05-01), Lewis et al.
patent: 5434134 (1995-07-01), Gluckman et al.
patent: 5527776 (1996-06-01), Carlino et al.
patent: 5527789 (1996-06-01), Nyce
patent: 5534493 (1996-07-01), Gluckman et al.
patent: 5629286 (1997-05-01), Brewitt
patent: 5736515 (1998-04-01), Bengtsson et al.
patent: 5744139 (1998-04-01), Kudsk
Su-Ming HSU et al. "Cytokins in Malignant Lymph-omas: Review and Prospective Evolution" Journal of Biomedical Sciences 3(1), 1-13, 1996.
David N. Orth et al., "Williams Textbook of Endocrinology" Ed. Wilson et al., 8th ed. W.B. Saunders Co. Philadelphia U.S., pp. 499-505. 589, 590, 1992.
Aberg et al., "Increases in tissue levels of ubiquionone in association with peroxisome proliferation" Chem. Biol. Inter. (1996) 99:205-218.
Almenoff et al., "Pulmonary function survey in spinal cord injury: Influences of smoking and level and completeness of injury" Lung (1995) 173:297-306.
Almenoff et al., "Bronchodilatory effects of ipratropium bromide in patients with tetraplegia" Paraplegia (1995) 33:274-277.
Andrews et al., "Contemporary mangement of depression" Am. J. Med. (1994) 97:6A-24S-6A-32S.
Baker et al., "Effects of an Igf1 gene null mutation on mouse reproduction" Mol. Endrocrinol. (1996) 10:903-918.
Bauman et al., "Blunted growth hormone response to intravenous arginine in subjects with a spinal cord injury" Horm. Metab. Res. (1994) 26:152-156.
Bauman et al., "Chronic baclofen therapy improves the blunted growth hormone response to intravenous arginine in subjects with spinal cord injury" J. Clin. Endocrinol. Metab. (1994) 78:1135-1138.
Bauman et al., "Disorders of carbohydrate and lipid metabolism in veterans with paraplegia or quadriplegia: A model of premature aging" Metabolism (1994) 43:749-756.
Baxter et al., "Growth hormone-dependent insulin-like growth factor (IGF) binding protein from human plasma differs from other human IGF binding proteins" Biochem. Biophys. Res. Comm. (1986) 139:1256-1261.
Bennett et al., "A double blind placebo controlled study of growth hormone therapy in fibromyalgia" J. Musculoskeletal Pain (1995) Abstract enclosed from Supplement: Myopain '95 Jul. 30-Aug. 3, 1995, San Antonio, Texas, p. 110.
Blum et al., "Plasma IGFBP-3 levels as clinical indicators" Modern Concepts in Insulin-Like Growth Factors (1991) E. M. Spencer, ed., Elsevier, New York, pp. 381-393.
Castro-Alamancos et al., "Long-term depression of glutamate-induced .gamma.-aminobutyric acid release in cerebellum by insulin-like growth factor I" Proc. Natl. Acad. Sci. USA (1993) 90:7386-7390.
Castro-Alamancos et al., "Learning of the conditioned eye-blink response is impaired by an antisense insulin-like growth factor I oligonucleotide" Proc. Natl. Acad. Sci. USA (1994) 91:10203-10207.
Chuzel et al., Transcriptional regulation of the lutropin/human choriogonadotropin receptor and three enzymes of steroidogenesis by growth factors Eur. J. Biochem. (1996) 239:8-16.
Daynes et al., "Altered regulation of IL-6 production with normal aging" J. Immunol. (1993) 150:5219-5230.
Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition: DSM-IV.sup..TM., American Psychiatric Association, Washington, D.C. Title page and table of contents.
Ferraccioli et al., "Somatomedin C (insulin-like growth factor I) levels decrease acute changes of stress related hormones. Relevance for fibromyalgia" J. Rheumatol. (1994) 21:1332-1334.
Flood et al., "Memory-enhancing effects in male mice of pregnenolone and steroids metabolically dervied from it" Proc. Natl. Acad. Sci. USA (1992) 89:1567-1571.
Flood et al., "Pregnenolone sulfate enhances post-training memory processes when injected in very low doses into limbic system structures: The amygdala is by far the most sensitive" Proc. Natl. Acad. Sci. USA (1995) 92:10806-10810.
Geders et al., "The effect of cisapride on segmental colonic transit time in patients with spinal cord injury" Am. J. Gastroenterol. (1995) 90:285-289.
Holsboer et al., "Steroid effects on central neurons and implications for psychiatric and neurological disorders" Ann. N.Y. Acad. Sci. (1994) 746:345-361.
Huang et al., "Suppression of the hypothalamus-pituitary somatotrope axis in men with spinal cord injuries" Metabolism (1995) 44:1116-1120.
Kahn et al., "Loss of high-affinity prostacyclin receptors in platelets and the lack of prostaglandin-induced inhibition of platelet-stimulated thrombin generation in subjects with spinal cord injury" Proc. Natl. Acad. Sci. USA (1996) 92:245-249.
Kamikubo et al., "Similar nuclear factors mediate stimulation of rat thyroglobulin gene transcription by thyrotropin and insulin-like growth factor-1" Mol. Endocrinol. (1990) 4:2021-2029.
Katagiri et al., "The role of cytochrome b.sub.5 in the biosynthesis of androgens by human P450c17" Arch. Biochem. Biophys. (1995) 317:343-347.
Mondadori et al., "Delayed emergence of effects of memory-enhancing drugs: Implications for the dynamics of long-term memory" Proc. Natl. Acad. Sci. USA (1994) 91:2041-2045.
Morales et al., "Effects of replacement dose of dehydroepiandrosterone in men and women of advancing age" J. Clin. Endocrinol. Metab. (1994) 78:1360-1367.
Nathorst-Boos et al., "Is a sexual life influenced by transdermal estrogen therapy?" Acta Obstet. Gynecol. Scand. (1993) 72:656-660.
Nathorst-Boos et al., "Elective ovarian removal and estrogen replacement therapy-effects on sexual life, psychological well-being and androgen status" J. Psychosom. Obstet. Gynaecol. (1993) 14:283-293.
Rinderknecht et al., "Polypeptides with nonsuppressible insulin-like and cell-growth promoting activities in human serum: Isolation, chemical characterization, and some biological properties of forms I and II" Proc. Natl. Acad. Sci. USA (1976) 73:2365-2369.
Robel et al., Dehydroepiandrosterone (DHEA) is a neuroactive neurosteroidAnn. N.Y. Acad. Sci. (1995) 774:82-110.
Shetty et al., "Hyposomatomedinemia in quadrigplegic men" Am. J. Med. Sci. (1993) 305:95-100.
Sommer et al., "Molecular genetics and actions of recombinant insulin-like growth factor binding protein-3" Modern Concepts of Insulin-Like Growth Factors (1991) E.M. Spencer, ed., Elsevier, New York, pp. 715-728.
Tallis, Primary hypothyroidism: A case for vigilance in the psychological treatment of depression Brit. J. Clin. Psychol. (1993) 32:261-270.
Tsitouras et al., "Serum testosterone and growth homone/insulin-like growth factor-1 in adults with spinal cord injury" Horm. Metab. Res. 1995) 27:287-292.
Wolfe et al., "The American College of Rheumatology 1990 criteria for the classification of fibromyalgia" Arthritis Rheum. (1990) 33:160-172.
Yasin et al., "Melatonin and its analogs inhi

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