Method for treating the epithelium of bodily orifices with chlor

Details Method for treating the epithelium of bodily orifices with chlor Method for treating the epithelium of bodily orifices with chlor

1998-04-27

1999-05-11

Bawa, Raj

Drug, bio-affecting and body treating compositions

Topical body preparation containing solid synthetic organic...

424 45, 424 49, 424 52, 424 53, 424 57, 424427, 424434, 424437, 424430, 424661, 424673, 424676, 424DIG15, 514944, 514945, 514966, 514967, 514968, A61K9/10

Patent

active

059025751

ABSTRACT:
A stable solution, cream, salve, or spray composition containing chlorine dioxide and a phosphate, such as disodium hydrogen phosphate, sodium dihydrogen phosphate, trisodium phosphate, and sodium monofluorophosphate, is disclosed for the prevention and treatment of abnormal conditions of the epithelium of bodily orifices. Examples of such abnormal conditions of the epithelium of the rectal, vaginal, urethral, oral, nasal, ocular, and auditory canal orifices brought about by any of leukoplakia, hairy leukoplakia, vaginitis, endometriosis, Candida Albicans, Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, Pseudomonades, Candida species, and leukoplakia vulvae. The preferred concentration ranges are between about 0.005%-2.0% chlorine dioxide, and between about 0.02%-3.0% phosphate. The phosphate compound retards escape of chlorine dioxide in the pH range of 6.0 to 7.4, at which pH chlorine dioxide becomes activated and releases sufficient chlorine dioxide to reduce motility and become lethal to the involved micro-organisms.

REFERENCES:
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