Method for treating severe tinnitus

Surgery – Controlled release therapeutic device or system – Implanted dynamic device or system

Reexamination Certificate

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C128S898000

Reexamination Certificate

active

06969383

ABSTRACT:
A method for treating severe tinnitus is disclosed. The method of the present invention comprises implanting a catheter into a patient and administering a drug formulation or fluid comprising a therapeutic agent intrathecally into the patient's cerebrospinal fluid.

REFERENCES:
patent: 4445500 (1984-05-01), Osterholm
patent: 5496369 (1996-03-01), Howard, III
patent: 5676655 (1997-10-01), Howard, III et al.
patent: 5711316 (1998-01-01), Elsberry et al.
patent: 5713847 (1998-02-01), Howard, III et al.
patent: 5863941 (1999-01-01), Liedtke
patent: 6265379 (2001-07-01), Donovan
patent: 6309410 (2001-10-01), Kuzma et al.
patent: 6358926 (2002-03-01), Donovan
patent: 6656172 (2003-12-01), Hildebrand
patent: 2002/0156512 (2002-10-01), Borkan
Kaneko, Megumi et al., Intrathecally Administered Gabapentin Inhibits Formalin-Evoked Nociception and the Expression of Fos-Like Immunoreactivity in the Spinal Cord of the Rat, J. Pharmacol Exp Ther, vol. 292, Issue 2, 743-751, Feb. 2000.
Menkes, D B, et al.; “Sodium Valproate for Tinnitus”; Journal of Neurology Neurosurgery & Psychiarty, XX, XX, vol. 65, No. 5, (Nov. 1998) p. 803.
Simpson, J J, et al.; “A Review of Evidence in Support of a Role for 5-HT in the Perception of Tinnitus”; Hearing Research 2000 Netherlands, vol. 145, No. 1-2, 2000, pp. 1-7.
Uno, I. et al.; “A Rare Complication of Stellate Ganglion Block a Case Report”; Practica Otologica Kyoto; vol. 77, No. 12, 1984, pp. 2515-2519.
Gentili, Marc E.; “Epidural Fibrin Glue Injection Stops Postdural Puncture Headache in Patient With Long-Term Intrathecal Catheterization.”; Regional Anesthesia and Pain Medicine, United States 2003; Jan.-Feb., vol. 28, No. 1; (Jan. 2003), p. 70.
Coffey, R J, et al.; “Abrupt Intrathecal Baciofen Withdrawal: Management of Potentially Life-Threatening Sequelae”; Neuromodulation 2001 United States, vol. 4, No. 4, 2001, pp. 142-146.
Lewis, J.E., S.D.G. Stephens, et al, “Tinnitus and suicide.” Jul. 7, 1993, pp. 50-54, vol. 19, Clin Ototaryngol.
McFadden, D., Tinnitus: Facts, Theories, and Treatments, 1982, pp. 1-9, National Academy Press, Washington D.C.
Sataloff, J., R.T. Sataloff, et al., “Tinnitus and vertigo in healthy senior citizens without a history of noise exposure.” Mar. 1987, pp. 87-89, vol. 2, Thieme Medical Publishers, Inc., New York, NY.
Axelsson, A. and A. Ringdahl, “Tinnitus-a study of its prevalence and characteristics.”, 1989, pp. 53-56, vol. 23, British Journal of Audiology.
Coles, R. R. A., Thompson, et al., “Intra-tympanic injections in the treatment of tinnitus.”, 1992, pp. 240-242, vol. 17, Clin Otolaryngol.
Dobie, R.A., “A review of randomized clinical trials in tinnitus.”, The Laryngoscope, Aug. 1999, pp. 1202-1211, Lippincott Williams & Wilkins, Inc., Philadelphia.
Lockwood, A.H., R.J. Salvi, et al, “The functional neuroanatomy of tinnitus: Evidence for limbic system links and neural plasticity.”, Jan., 1998, Neurology, pp. 114-120, vol. 50, American Academy of Neurology.
Moller, A.R., “Symptoms and signs caused by neural plasticity.” Neurological Research, Sep., 2001, pp. 565-572, vol. 23, Forefront Publishing Group.
Den Hartigh, J., C. G. J. M. Hilders, et al., “Tinnitus suppression by Intravanous lidocaine in relation to its plasma concentration.” Clinical Pharmacology & Therapeutics, Oct. 1993, pp. 415-420, vol. 54 No. 4, Mosby-Year Book, Inc.
Ochi, K. and J.J. Eggermont, “Effects of salicylate on neural activity in cat primary auditory cortex.” Hearing Research, 1996, pp. 63-76, vol. 95, Elsevier Science B.V.
Caspary, D.M., J. C.Milbrandt, et al., “Central Auditory Aging: GABA Changes in the Inferior Colliculus.”Experimental Gerontology, 1995, pp. 349-360, vol. 30 Nos. 3/4, Elsevier Science Ltd. , USA.
McGeer, E. G. and P. L. McGeer, “Age Changes in the Human for Some Enzymes Associated with Metabolism of the Catecholamines, GABA and Acetycholine.” Neurobiology of Aging, 1975, pp. 287-305, Plenum Press, New York.
Raza, A., J. C. Milbrandt, et al., “Age-Related Changes in Brainstem Auditory Neurotransmitters: Measures of GABA and Acetylcholine Function.” Hearing Research, 1994, pp. 221-230, vol. 77, Elsevier Science B. V.
Araki, T., H. Kato, et al., “Selective changes of neurotransmitter receptors in middle-aged gerbil brain.” Neurochem. Int., 1993, pp. 541-548, vol. 23 No. 6, Pergamon Press Ltd.
Mildbrandt, J. C., R. L. Albin, et al., “Age-Related Decrease in GABAaReceptor Binding in the Fischer 344 Rat Inferior Colliculus.” Neurobiology of Aging, 1994, pp. 699-703, vol. 15 No. 6, Elsevier Science Ltd., USA.
Moller, A. R., M. B. Moller, et al., “Some Forms of Tinnitus May Involve the Extralemniscal Auditory Pathway.” Laryngoscope, Oct 1992, pp. 1165-1171.
Szczrpaniak, W. S. and A. R. Moller, “Effects of L-Baclofen and D-Bachlofen on the Auditory System: A Study of Click-Evoked Potentials From the Inferior Colliculus in the Rat.” Ann Otol Rhinol Laryngol, 1995, pp. 399-404.
Szczrpaniak, W. S. and A. R. Moller, “Effects of (-) baclofen, clonazepam, and diazepam on tone exposure-induced hyperexcitability of the inferior colliculus in the rat: possible therapeutic implications for pharmacological management of tinnitus and hyperacusis.” Hearing Research, 1996, pp. 46-53, Elsevier Science B.V.
Lees, A. J., C. R. Clarke et al., “Hallucinations After Withdrawal of Baclofen.” The Lancet, Apr. 16, 1977.
Zapp, J. J., “Gabapentin for the treatment of tinnitus: A case report.” ENT-Ear, Nose & Throat Journal, Feb. 2001, pp. 114-116.
Kuzniecky, R. S. Ho, et al., “Modulation of cerebral GABA by topiramate, lamotrigine, and gabapentin in healthy adults.” Neurology, Feb. 2002, pp. 368-372, AAN Enterprises, Inc.
Petroff, O. A., F. Hyder, et al., “Effects of Gabapentin on Brain GABA, Homocamosine, and Pyrrolidinone in Epilepsy Patients.” Epilepsia, 2000, pp. 675-680, Lippincott Williams & Wilkins, Inc., Baltimore.
Westerberg, B. D., J. B. Roberson, et al., “A double-blind placebo-controlled trial of baclofen in the treatment of tinnitus.” The American Journal of Otology, 1996, pp. 896-903, The American Journal of Otology, Inc.
Coffey, R. J., D. Cahill, et al., “Intrathecal baclofen for intractable spasticity of spinal origin: results of a long-term multicenter study.” J Neurosurg, Feb. 1993, pp. 226-232, vol. 78.
Meythaler, J. M., S. Guin-Renfroe, et al., “Continuously Infused Intrathecal Baclofen for Spastic/Dystonic Hempiplegia.” American Journal of Physical Medicine & Rehabilitation, 1999, pp. 155-161, No. 9, Lippincott Williams & Wilkins, Inc.
Penn, R. D., S. M. Savoy, et al., “Intrathecal Baclofen for Severe Spinal Spasticity.” New England Journal of Medicine, Jun. 8, 1989, pp. 1571-1521, vol. 320.
Knutsson, E., U. Lindblom, et al., “Plasma and Cerebrospinal Fluid Levels of Baclofen (Lioresal®) at Optimal Therapeutic Responses in Spastic Paresis.” Journal of the neurological Sciences, 1974, pp. 473-484, vol. 23, Elsevier Scientific Publishing Company, Netherlands.
Kroin, J. S., “Intrathecal Drug Administration.” Clin. Pharmacokinet. 1992, pp. 319-326, vol. 22 (5), Adis International Limited.
Kroin, J. S. and R.D. Penn, “Cerebrospinal fluid pharmacokinetics of lumbar intrathecal baclofen”, 1991, pp. 67-77, Parthenon Publishing.
Muller, H., J. Zierski, et al. “Pharmacokinetics of Intrathecal Baclofen.” 1998, pp. 223-226, Springer-Verlag.
MilBrandt, JC, et al., “GAD levels and muscimol binding in rat inferior colliculus following acoustic trauma.” Hearing Research, 2000, pp. 251-260, vol. 147 (1-2), Elsevier Science B.V.
Caspary, D.M., T.M. Holder, et al., “Age-Related Changes in GABAAReceptor Subunit Composition and Fun

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