Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-05-17
2005-05-17
Spivack, Phyllis G. (Department: 1614)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
Reexamination Certificate
active
06894069
ABSTRACT:
A selective inhibitor of neuronal nitric oxide synthase (nNOS) and of inducible nitric oxide synthase (iNOS), which does not substantially inhibit endothelial nitric oxide synthase (eNOS), can be effectively used for the treatment, in human or other mammalian neonates, of the effects of complications during childbirth. Such effects include perinatal asphyxia and hypoxia-ischemia. A very useful example of such a selective inhibitor is 2-iminobiotin.
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K. Kumar, “Hypoxic-Ischemic Brain Damage in Perinatal Age Group”, Indian Journal of Pediatrics, 1999, pp. 475-482, XP-000937788.
Groenendaal Floris
Peetres Cacha Marie Pétronelle Cathérine Dorotheé
Van Bel Frank
Spivack Phyllis G.
Universitair Medisch Centrum
Young & Thompson
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