Surgery – Blood drawn and replaced or treated and returned to body
Patent
1995-05-01
1998-03-31
Buiz, Michael Powell
Surgery
Blood drawn and replaced or treated and returned to body
604 52, 435 78, 424530, A61M 3700
Patent
active
057332541
ABSTRACT:
Immune thrombocytopenic purpura is treated by removal of IgG and circulating immune complexes from the patient's blood. Removal is accomplished by exposing the blood or blood plasma to an immunoadsorbent capable of removing IgG and its complexes. The immunoadsorbent comprises a suitable solid phase coupled to a receptor capable of binding IgG and its complexes, such as protein A. The IgG and its complexes are then removed by the extracorporeal exposure of the patient's blood to the immunoadsorbent, either in a continuous or discontinuous process. In the continuous process, the blood is removed in a steady flow from the patient, separated into its plasma and cellular components, the plasma treated, and the combined cellular components and treated plasma reinfused to the patient. In the discontinuous method, a small volume of blood is removed from the patient, the entire volume separated into plasma and cellular components, the plasma treated, and the entire volume of treated plasma returned to the patient, usually after the cellular components have been returned.
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Balint, Jr. Joseph P.
Jones Frank R.
Snyder Harry W.
Buiz Michael Powell
Cypress Bioscience, Inc.
Nguyen At
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