Method for treating patients for radiation exposure

Details Method for treating patients for radiation exposure Method for treating patients for radiation exposure

2007-02-13

2007-02-13

Spivack, Phyllis G. (Department: 1614)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

C514S109000, C514S126000, C514S127000, C514S517000, C514S578000, C514S707000

Reexamination Certificate

active

10002526

ABSTRACT:
This invention relates to a method of treating a patient suffering from ionizing radiation exposure, or of treating a patient about to undergo ionizing radiation therapy. The method includes administering to a patient in need of treatment an effective amount of a thiol or reducible disulfide compound according to the formula set forth in the specification.

REFERENCES:
patent: 5770576 (1998-06-01), Morozov et al.
patent: 5789000 (1998-08-01), Hausheer et al.
Plowman et al., Lancet, 1(8525), p. 167 (Jan. 17, 1987).
van den Broeke et al., J. Photochem. Photobiol., 17(3), pp. 279-286 (1993).
Facts & Comparisons, 48thedition (1994) p. 2841.
Norbert Brock et al., “Studies on the Urotoxicity of Oxazaphosphorine Cytostatics and its Prevention. 2. Comparative Study on the Uroprotective Efficacy of Thiols and Other Sulfur Compounds,”Eur. J. Cancer Clin. Oncol., 17:1155-1163 (1981).
Theodore L. Phillips, MD., “Chemical Modification of Radiation Effects,”Cancer39:987-999 (1977).

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