Method for treating painful conditions of the anal region and co

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514 23, 514331, 514400, 514537, 514626, 514627, 514651, A61K 31505

Patent

active

061178772

ABSTRACT:
Method and composition for treating painful conditions of the anorectal region. The compositions include a combination of an .alpha.-adrenergic blocker and sucralfate, a combination of .alpha.-adrenergic blocker and lidocaine, and a combination of an .alpha.-adrenergic blocker, lidocaine, and sucralfate. Alternatively, the composition may contain only an .alpha.-adrenergic blocker. Additional active ingredients for reduction of anal pain may be added to the composition, particularly capsaicin. The compositions may be included in a petrolatum base along with a water soluble lubricant. These compositions have been found effective in treating painful conditions in the anal region, such as anal fissures, inflamed or recently thrombosed hemorrhoids, and chronic anal pain.

REFERENCES:
patent: 4945084 (1990-07-01), Packman
patent: 5447947 (1995-09-01), Campbell
patent: 5854291 (1998-12-01), Laughlin et al.
CA 128: 119698, Samejima et al., JP 10001331 A2, Abstract, Jan. 6, 1998.

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