Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Reexamination Certificate
2005-04-19
2005-04-19
Wilson, James O. (Department: 1623)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
C514S012200, C514S051000, C514S277000, C514S851000, C536S026100, C536S025600, C424S045000, C424S427000, C128S898000, C623S004100, C606S107000
Reexamination Certificate
active
06881725
ABSTRACT:
The present invention is directed to a method of treating pain. The method comprises administering to a subject a pharmaceutical composition comprising an effective amount of a P2X receptor antagonist. The methods of the present invention are useful in reducing pain, such as traumatic pain, neuropathic pain, organ pain and pain associated with diseases. The P2X receptor antagonists particularly useful for this invention are mononucleoside polyphosphate derivatives or dinucleoside polyphosphate derivatives of general Formula I. The compounds of the present method can be used alone to treat pain. The compounds of the present method can also be used in conjunction with other therapeutic agents or adjunctive therapies commonly used to treat pain, thus enhancing the overall pain-reducing effect in a subject in need of such treatment.
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Crean Christopher S.
Peterson Ward M.
Yerxa Benjamin R.
Inspire Pharmaceuticals Inc.
Khare Devesh
Kung Viola T.
Wilson James O.
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