Drug – bio-affecting and body treating compositions – Lymphokine – Interleukin
Patent
1996-10-04
1998-01-13
Ulm, John
Drug, bio-affecting and body treating compositions
Lymphokine
Interleukin
514 2, 514 8, 514 12, 514885, 530351, 435 6952, 435325, 4352523, 4353201, A61K 3820, C12N 1524, C07K 1454
Patent
active
057076162
ABSTRACT:
Nucleic acid sequences which encode biologically active ETF, expression vectors which direct the expression of ETF, ETF polypeptides, antibodies which specifically bind ETF and processes for preparing the same are disclosed. Also disclosed are methods for treating or preventing gastrointestinal diseases and HIV or HIV-associated diseases.
REFERENCES:
Grabstein et al., "Cloning of a T Cell Growth Factor That Interacs with the .beta. Chain of the Interleukin-2 Receptor," Science 264:965-968, 1994.
McMahan et al., "A novel IL-1 receptor, cloned from B Cells by mammalian expression, is expressed in many cell types," EMBO Journal 10(10):2821-2832, 1991.
Anderson Dirk M.
Eisenman June R.
Fung Victor
Grabstein Kenneth H.
Rauch Charles
Immunex Corporation
Mertz Prema
Ulm John
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