Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1988-06-07
1989-07-18
Waddell, Frederick E.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
A61K 314
Patent
active
048494429
ABSTRACT:
The present invention provides a novel method for preventing deep vein thrombosis comprising the adminstration of lipoxygenase inhibitors of Formula I ##STR1##
REFERENCES:
patent: 3948958 (1976-04-01), Rapoport et al.
patent: 4199531 (1980-04-01), Terao et al.
patent: 4320065 (1982-03-01), Dotz
patent: 4338312 (1983-06-01), Terao et al.
patent: 4358461 (1982-11-01), Maki et al.
patent: 4374775 (1983-02-01), Dotz
patent: 4393075 (1983-07-01), Terao et al.
G. A. Higgs et al., A New Approach to Anti-Inflammatory Drugs, Biochem. Pharmacol., 28:1959-1961 (1979).
B. Samuelsson et al., Prostaglandins and Throboxanes, Ann. Rev. Biochem. 47:997-1029 (1978).
W. D. Wulff et al., Abstracts 88 and 89, American Chemical Society Meeting, Washington, D.C. (Aug. 18-19, 1983).
K. H. Dotz et al., XXIV Synthese von Naphthol-Derivaten Aus Carbonyl-Carben-Komplexen und Alkinen: Regioselektiver Einbau Des Alkins in Das Naphthalin-Gerust, J. of Organometal. Chem., 247:187-201 (1983).
K. Buggle et al., Decomposition Products of Pyrazolines formed from 3-Alkylthioninden-1-ibes abd Duazomethane, J. Chem. Soc. Perkin Trans., I, 572-575 (1975).
K. H. Dotz, IX Carbenliganden, Carbonylliganden und Alkine Als Bausteine fur Isocyclische und Heterocyclische Systeme, J. Organomet. Chem., 140(2):177-186 (1977).
K. H. Dotz et al., Templat-Reaktionen an Chrom(O): Stereoselektive 110:1555-1563 (1977).
C. D. Synder et al., Synthesis of Menaquinone, J. Am. Chem. Soc., 96(26):-8046-8054 (1974).
F. M. Dean et al., Spirans. Part 11. A New Method for Generating o-Quinone Methides, and its Applications to the Synthesis of Spirochromans, J. Chem. Soc., Perkin Trans. I, 2289-2294 (1977).
O. Goncalves de Lima et al., Atividade Antimicrobiana Dos Compostos Intermediarios e do Produto de Sintese 7-metox--3,9-dimetil-1-oxa fenaleno, Rev. Inst. Antibiot., Univ. Recife, 5N(1/2):3-9 (1963).
K. H. Dotz et al., Templat-Reaktionen an Chrom(O): Steroselektive Synthese Kondensierter Aromatischer Liganden aus Pentacarbonyl-Carben-Chrom-Komplexen und Alkinen, Chem. Ber., 111:2517-2526 (1978).
M. Shiraishi et al., Studies on the Synthesis of 5-Lipoxygenase Inhibitors, J. Pharm. Syn., 7 (No. 5):s--95 (1984).
M. Shiraishi and S. Terao, Quinones, Part 3, Synthesis of Quinone Derivatives having Ethylenic and Acetylenic Bonds: Sepcific Inhibitors of the Formation of Leukotrienes and 5-Hydroxyicosa-6,8,11,14-tetraenoic Acid (5-HETE), J. Chem. Soc. Perkin Trans. I, 1591-1599 (1983).
Corneglio Donald L.
The Upjohn Company
Waddell Frederick E.
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